Advisor
Dr. Sanjay Batra
Second Advisor
2024
Department
Environmental Toxicology
Document Type
Presentation
Abstract
The Hippo signalling pathway is commonly recognized for its ability to regulate tissue growth organ size and cell proliferation by directly participating in inflammation. Nevertheless, recent studies indicate that the Hippo pathway can potentially impact inflammation indirectly by controlling processes like cell proliferation, differentiation, and tissue repair. Engineered nanoparticles, particularly single- or multi-walled carbon nanotubes (SWCNTs/MWCNTs), are commonly used in various products. Inhalation of these nanotubes carries health risks due to their large surface area and strong binding affinity for pollutants or biomolecules, which can affect immune and non-immune cell responses. Functionalization of CNTs with chemical groups further complicates their properties. However, the role of Hippo pathway in CNTs-induced lung inflammation has not yet been explored in detail.
Presentation Date
3-10-2024
Recommended Citation
Thakur, M.; Mutyala, D.; Bidarimath, N.; Kondati, R.; and Batra, S., "Hippo Pathway and Inflammation: Implications for Multiwalled-Carbon Nanotube Exposure." (2024). Student Presentations. 5.
https://digitalcommons.subr.edu/osp_studentpresentations/5